The Absorptive Capacity Theory was used as the theoretical lens for this study to help analyze how organizations absorb new knowledge using social media tools and applications. A survey of fashion designers and employees numbering 196 was carried out in 55 fashion firms whereas two fashion firms were used in a case study. Data analysis was performed using the Structural Equation Modelling. The findings from the study suggest that Ghanaian fashion designers do not intensively use social media to assimilate knowledge but rather to acquire, transform and exploit knowledge. The popular social media applications include; Facebook, Twitter, and Instagram. Facebook, for instance, is used on a daily basis by most Ghanaian fashion designers. Fashion designers use social media to acquire, transform and exploit knowledge through research, interaction, communication, and marketing with suppliers, customers, and other fashion designers. Future research can extend this work by looking at organizational learning and social media use in a different industry.