The quality of domestic water supplied to households in the Effutu Municipality was evaluated using twenty-two physico-chemical parameters. Pearson rank correlation coefficient and an independent one tailed student t-test were used to analyse the results. Except for colour, no significant statistical differences were observed between the samples from the headworks (HW) and the households. The correlation between the headworks (Hw) and household in terms of the other parameters varied from 1.0. Generally, water samples from both the Hw and the households were potable by WHO standards. However, the presence of total coliform ranging from 10.0 cfu/100.0mL at V7 (Pupil) 489.25 cfu/100.0 mL at V1 (Roman school) and faecal coliform of 0.75 cfu/100.0 mL at V8 (New Winneba) to 20.50 cfu/100.0 mL at V4 (Junction) in some household samples were of much concern as these levels have a high tendency to compromise the health status of consumers. Occasional breaks in pipe-lines and water rationing were found to be some of the causes of external waters infiltrating into the distribution systems. Passing pipelines through gutters and illegal connections by individuals should be discouraged by Ghana Water Company (GWC) Ltd.

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