This paper reviewed issues pending current trend in the fashion industry while assessing the readiness of fashion institutions in Ghana for the absorption of industrial revolution popularly referred to as industry 4.0. With the invention of new technologies the fashion industry has improved significantly over the years. However, the role of the fashion industry in the achievement of Industry 4.0 in most developing countries seem to be challenged by several factors which ultimately impacts on the ability of the industry to effectively incorporate features of Industry 4.0 demands in its activities. With the focus on Ghana, the fashion industry is seemingly open to embrace new technologies in its production processes but lacks mainly the technical know-how and the industry specific accouterments needed to make the real changeover into Industry.