This study investigates the interplay between Occupational Health and Safety (OHS) practices,
employee commitment, and employee performance at manufacturing companies. A quantitative
approach using correlation and regression analyses assessed relationships between variables. Data
were collected from 115 employees across three manufacturing companies in Ghana’s Awutu Senya
District. OHS practices positively influence both employee commitment and performance, with
commitment partially mediating this relationship. This suggests that a safety-focused environment leads
to a more committed and high-performing workforce. These findings hold significant practical
implications for manufacturing companies. By prioritizing comprehensive OHS initiatives, organizations
can cultivate a safer and more supportive work environment, which leads to a more engaged and
productive workforce. This study examines the under-explored mediating role of employee commitment
in the OHS-performance relationship within the manufacturing industry in Ghana. By doing so, it extends
knowledge and offers insights for optimizing workplace safety, employee well-being, and organizational
success.